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Erectile Dysfunction / Premature Ejaculation News From Medical News Today Latest Erectile Dysfunction / Premature Ejaculation News From Medical News Today. Researchers Examine Safety Of Internet Prescriber Service Providing Erectile Dysfunction Medications Online Internet shopping today offers many benefits. You can research a product in the privacy of your own home and purchase most anything by clicking a mouse. Causes For Sexual Dysfunction Change As People Age - Earlier Experiences With Multiple Partners And STDs Take Their Toll Sexual dysfunction is not an inevitable part of aging, but it is strongly related a number of factors, such as mental and physical health, demographics and lifetime experiences, many of which are interrelated, according to a new study by researchers at the University of Chicago. The study, funded by the National Institutes of Health, found that a history of sexually transmitted disease also has an impact on sexual health later in life. Medical Management And Surgical Management Of Peyronie's Disease UroToday.com Peyronie's disease is a scarring phenomenon affecting the tunica albuginea of the penis. Scar tissue forms "plaques" that can result in pain with erection, penile deviation, penile shortening, indentation, and/or erectile dysfunction. It is associated with difficulty with sexual intercourse and as such it is associated with loss of self-esteem and depression on the part of the patient and often on the part of the patient's partner. Penile Prostheses For The Treatment Of Erectile Dysfunction UroToday.com - While erectile dysfunction has been described since ancient times, adequate treatment has only been available for the last three decades. Modern penile prosthetic devices were first developed in the early 1970s when Small et al. along with Scott et al. reported the implantation of penile prosthetic devices into the corpora cavernosa to fill the corpora cavernosa and provide a physiologically functional erection with good cosmetic results. No-Nose Bicycle Saddles Improve Penile Sensation And Erectile Function In Bicycling Police Officers An innovative study appearing in the August issue of The Journal of Sexual Medicine examined, for the first time, if noseless bicycle saddles would be an effective intervention for alleviating deleterious health effects, erectile dysfunction and groin numbness, caused by bicycling on the traditional saddle with a protruding nose extension. Health Canada Advises Consumers Not To Use Rize 2 The Occasion Capsules Or Any Unauthorized Erectile Dysfunction Products Health Canada is warning consumers not to use Rize 2 The Occasion capsules (Rize2), an unauthorized product promoted for the treatment of erectile dysfunction, because it may pose serious health risks. Rize 2 contains an undeclared pharmaceutical ingredient similar to the prescription drug sildenafil which should only be used under the supervision of a health care professional. Erectile Dysfunction And The Prostate: What Are The Connections? UroToday.com - Prostate cancer is the leading malignancy in American men and causes more than 60,000 deaths annually. Treatment of prostate cancer with either surgery, radiation therapy, cryotherapy or medical treatment is associated with significant life altering morbidity. Both incontinence and erectile dysfunction (ED) are too often sequelae of these treatment alternatives. ED can be a significant complication and can alter the life of both the prostate cancer patient and his partner. Suspended Pharmacist Is Fined £3,000 For Illegal Sale And Supply Of Viagra Hitendra Patel (41), a suspended pharmacist, of 2 St Mary's Copse, St Mary's Road, Worcester Park, Surrey KT4 7LA was fined £3,000 and given a confiscation order of over £200,000 at Kingston Crown Court on 25 July 2008 for illegally selling and supplying the erectile dysfunction medicine Viagra. The sentence follows a prosecution by the Medicines and Healthcare products Regulatory Agency (MHRA). The case began in 2003. NexMed Receives FDA Response For Erectile Dysfunction Product NexMed, Inc. (Nasdaq: NEXM), announced the receipt of a non approvable letter from the U.S. Food and Drug Administration (FDA) in response to its New Drug Application (NDA) for its topical treatment for erectile dysfunction (ED). The major regulatory issues raised by the FDA were related to the results of the transgenic mouse carcinogenicity study which NexMed completed in 2002. Study Confirms That Levitra® On Demand Is Effective In Patients With ED After Nerve-sparing Prostatectomy A study published in the European Urology journal demonstrated that Levitra® (vardenafil, HCI) is highly efficacious in men with erectile dysfunction (ED) even shortly after radical nerve-sparing prostatectomy. This landmark study conducted by Bayer Schering Pharma was a double-blind, randomized, placebo-controlled multicentre study, the largest of its kind until. Federal Authorities Seize Xiadafil VIP Tablets After Company Refuses To Recall Product, USA At the request of the U.S. Food and Drug Administration, U.S. Marshals seized nearly $74,000 worth of Xiadafil VIP tablets, Lots 6K029 and 6K209-SEI, distributed by SEI Pharmaceuticals, Inc. of Miami, Fla. Although marketed as a dietary supplement to treat erectile dysfunction (ED) and for sexual enhancement, these lots represent an illegally marketed drug containing an undeclared ingredient. The ED Conversation Dilemma: Forty Percent Of Men With ED Don't Talk To Their Doctor, Survey Finds A new survey reveals that while 82 percent of men with erectile dysfunction (ED) surveyed recognize it as an indicator of other health conditions, such as heart disease and diabetes, nearly 40 percent have never discussed the condition with their doctors. Men Unaware Of Erectile Dysfunction Risk A new survey shows that only ten per cent of men in their early to mid 40s know they may experience erection problems in the next decade, even though evidence suggests that the problem affects 40 per cent of men over the age of 40. Most men surveyed were unaware that erectile dysfunction (ED) may be a warning sign that they could have a serious underlying condition, such as diabetes or heart disease. Male Cyclists Risk Sexual Problems If They Don't Choose The Right Bike Men who take up cycling in an effort to stay fit, do their bit for the environment or avoid spiralling motoring costs, could be harming their health if they don't choose the right bicycle. That's the stark warning from consultant urological surgeon Mr Vinod Nargund from St Bartholomew's and Homerton Hospitals, London, in the urology journal BJU International. Peyronie's Disease: Characteristics & Treatments Peyronie's disease is characterized by a plaque, or hard lump, that develops on the upper or lower side of the penis in layers containing erectile tissue. It starts with an inflammation and can develop into a hardened scar. Symptoms may develop slowly or appear overnight and they consist of reduced flexibility, pain, curved and shortened penis during erection. The curvature of the penis generally leads to lowered self-esteem and makes sexual intercourse difficult, almost impossible. Erectile Dysfunction Lower In Men Who Have Intercourse More Often Having intercourse more often may help prevent the development of erectile dysfunction (ED). A study published in the July 2008 issue of The American Journal of Medicine reports that researchers have found that men who had intercourse more often were less likely to develop ED. Erectile Dysfunction After Plaque Incision And Grafting: Incidence And Predictors ORLANDO, FL (UroToday.com) - In this presentation, the group reported on the incidence and predictors of erectile dysfunction after plaque incision and grafting (PIG). 56 patients undergoing PIG were analyzed with pre and 6-month postoperative IIEF questionnaires. Mean duration of PD at the time of surgery was 23 months, mean plaque area was 4.7 cm2 and mean pre-op curvature was 52 degrees. 52 patients had grafting with Tutoplast, 4 with Surgisis. Viagra-Like Effects From Watermelon A cold slice of watermelon has long been a Fourth of July holiday staple. But according to recent studies, the juicy fruit may be better suited for Valentine's Day. That's because scientists say watermelon has ingredients that deliver Viagra-like effects to the body's blood vessels and may even increase libido. "The more we study watermelons, the more we realize just how amazing a fruit it is in providing natural enhancers to the human body," said Dr. Complications Of Penile Prosthesis Surgery ORLANDO, FL (UroToday.com) - Dr. Levine moderated this session on penile prosthetic (PP) surgery. Penile prosthetic devices have been implanted for over 40 years. The overall satisfaction with penile implants in one study was 83%, compared to 51% for PDE5 inhibitors and about 30% for injection therapy. About a 10% mechanical failure rate can be expected at 10 years, although it may decrease with newer devices. Adult Stem Cell Therapy For Erectile Dysfunction ORLANDO, FL (UroToday.com) - Dr. Tom Lue discussed autologous stem cell use for ED. He discussed that ability for the planarian species to regenerate any part of its body, but the salamander can only regenerate a limb. In man there are also stem cells, which are undifferentiated cells that have potential to also regenerate. In adipose tissue there are stem cells as demonstrated by immunohistochemistry, RT-PCR and Western blotting experiments. 40Over40: A New Campaign To Tackle Low Awareness Of Erectile Dysfunction And Its Health Implications In Younger Men A new survey of 1,000 men aged over 40, commissioned by Eli Lilly and Company Limited (Lilly UK) as part of a new erectile dysfunction awareness campaign, 40over40, reveals that just over 10% of men in their early 40s are aware that ED strikes regularly in the fourth decade even though evidence suggests that 40% of men aged 40 or over have some form of ED. 1 In 10 Men Suffer From Erectile Dysfunction Due To Work Related Stress New research has shown that 1 in 10 men experience erectile dysfunction (ED) and as many as 1 in 5 men suffer a loss of libido, as a result of work-related stress. These latest figures suggest that 90% of men have shown at least one clinical feature of stress due to work but only 54% of men know that stress from work may be the cause of their ED. Stress, either at work or home, is a known cause of ED and prolonged stress is associated with low testosterone levels. Men Treated For Prostate Cancer Experience High Levels Of Psychological Distress After Treatment Men treated for prostate cancer have high levels of psychological distress and many suffer ongoing sexual dysfunction and lower urinary tract symptoms, according to a survey of men in England designed to explore their supportive care needs. Prostate cancer is the commonest solid cancer in men, accounting for one in every four cancers diagnosed in males in England in 2004. Low Testosterone May Cause Health Problems That Lead To Erectile Dysfunction Men with erectile dysfunction should be examined for testosterone deficiency and the metabolic syndrome, because these conditions commonly occur together, a new study shows. The results will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco. "Erectile dysfunction is a portal into men's health," said the study's senior author, Aksam Yassin, MD, PhD, of the Clinic for Urology and Andrology of the Segeberger Clinics in Norderstedt, Germany. Phosphodiesterase Type 5 Inhibitors In Management Of Erectile Dysfunction Secondary To Treatments For Prostate Cancer UroToday.com - A group from the UK led by Bridget Candy report a meta-analysis in the BJU International on phosphodiesterase type 5 inhibitors (PDE5i) for the treatment of erectile dysfunction (ED) secondary to treatments for prostate cancer (CaP). Only randomized controlled trials were included and outcomes using validated scales such as the IIEF and SEP, successful sexual intercourse, time to effect, treatment satisfaction and health-related QOL were extracted.

Genetics News From Medical News Today Latest Genetics News From Medical News Today. QIAGEN Unveils Diagnostic Assay In The EU To Detect Genetic Variation Causing Adverse Reactions In AIDS Patients QIAGEN (Nasdaq: QGEN; Frankfurt Prime Standard: QIA) announced that it has introduced a new molecular diagnostic test to type the HLA-B*5701 allele, a genetic variation in the Human Leucocyte Antigen (HLA) system. HIV patients carrying the HLA-B*5701 marker have a 60% higher risk to develop hypersensitivity reaction (HSR) to Abacavir, which is a component of several widely marketed drugs inhibiting the reverse transcriptase of the HI virus. Attack Mechanism Of Illness-Inducing Bacterium Uncovered By UT Southwestern Researchers An infectious ocean-dwelling bacterium found in oysters and other shellfish kills its host's cells by causing them to burst, providing the invader with a nutrient-rich meal, researchers at UT Southwestern Medical Center have found. The bacterium, a relative of the one that causes cholera, co-opts and makes fatal a normal cell process that starving or stressed organisms use to disassemble and recycle expendable proteins into more vital metabolites. Facial Structures, Brain Abnormalities Studied To Reveal Formula For Detection Of Autism Recently, Harvard researchers reported that children with autism have a wide range of genetic defects, making it nearly impossible to develop a simple genetic test to identify the disorder. Now, University of Missouri researchers are studying 3-D imaging to reveal correlations in the facial features and brain structures of children with autism spectrum disorder (ASD), which will enable them to develop a formula for earlier detection of the disorder. Suppressing Disease-Causing Genes Is Now Within Reach Mount Sinai researchers have developed a new gene silencing technology that could be used to target genes that can lead to the development of certain diseases. This technology could pave the way for preventing diseases where gene dysfunction plays a role. The groundbreaking research was led by Ming-Ming Zhou, Ph.D., Professor and Chairman of the Department of Structural and Chemical Biology at Mount Sinai School of Medicine. Researchers Discover Technology That Silences Genes Mount Sinai researchers have developed a new gene silencing technology that could be used to target genes that can lead to the development of certain diseases. This technology could pave the way for preventing diseases where gene dysfunction plays a role. The groundbreaking research was led by Ming-Ming Zhou, Ph.D., Professor and Chairman of the Department of Structural and Chemical Biology at Mount Sinai School of Medicine. Blood Vessel Gene Influences Brain Size, Yale Researchers Find The size of a key area of the brain involved in memory and mood disorders is influenced by variation in a growth factor gene that influences blood vessel growth and has been widely studied in heart disease and cancer, Yale University researchers have found. Microbe Genome Emerges From Lake Sediment When entrepreneurial geneticist Craig Venter sailed around the world on his yacht sequencing samples of seawater, it was an ambitious project to use genetics to understand invisible ecological communities. But his scientific legacy was disappointing - a jumble of mystery DNA fragments belonging to thousands of unknown organisms. Gene Abnormalities Implicated In Bipolar Disorder - Sodium, Calcium Imbalances Linked To Manic Depressive Episodes The largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the balance of sodium and calcium in brain cells. Researchers supported in part by the National Institute of Mental Health, part of the National Institutes of Health, found an association between the disorder and variation in two genes that make components of channels that manage the flow of the elements into and out of cells, including neurons. Hydrogels Provide Scaffolding For Growth Of Bone Cells Hyaluronic hydrogels developed by Carnegie Mellon University researchers may provide a suitable scaffolding to enable bone regeneration. The hydrogels, created by Newell Washburn, Krzysztof Matyjaszewski and Jeffrey Hollinger, have proven to encourage the growth of preosteoblast cells, cells that aid the growth and development of bone. Doctoral student Sidi Bencherif presented this research, Sunday, Aug. 17 at the 236th national meeting of the American Chemical Society in Philadelphia. Lyme-Like Illness To Be Studied In Texas Tao Lin, D.V.M., and Steven J. Norris, Ph.D., both with the Department of Pathology and Laboratory Medicine at The University of Texas Medical School at Houston, have been named grant recipients of the Norman Hackerman Advanced Research Program (ARP) by the Texas Higher Education Coordinating Board. Scientists Make Precancerous Cells Self-Destruct By Amplifying Cell Death Signals When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the signals that tell these precancerous cells to die. The trick: Inactivating a protein that normally helps cells to avoid self-destruction. Model For Angelman Syndrome Developed By University Of Texas At Austin Biologists A model for studying the genetics of Angelman syndrome, a neurological disorder that causes mental retardation and other symptoms in one out of 15,000 births, has been developed by biologists at The University of Texas at Austin. Their research demonstrates that when a particular fruit fly gene, dube3a, is altered, the mutant flies show behavioral dysfunctions similar to those experienced by humans whose UBE3A gene doesn't function normally. Prototype Test For Predicting Clinical Outcome For Melanoma Patients - Gene Signature Prognostication Of Rapid Progression From Stage III To Stage IV Investigators from the Melbourne Center of the international Ludwig Institute for Cancer Research (LICR) and Pacific Edge Biotchnology Ltd today reported that they have developed a test to predict whether a patient will progress rapidly from Stage III melanoma to metastatic Stage IV cancer and death. Scientists Discover Major Genetic Cause Of Colorectal Cancer About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases. Scientists at Northwestern University's Feinberg School of Medicine and colleagues have discovered a genetic trait that is present in 10 to 20 percent of patients with colorectal cancer. Colon Cancer Linked To Unequal Gene Activity Researchers here have discovered that a subtle difference in the activity of a pair of genes may be responsible for one of every 10 colon-cancer cases. The work, led by researchers with the Human Cancer Genetics Program at Ohio State University's Comprehensive Cancer Center, is the first to link this particular gene conclusively as a cause of colon cancer, and it may provide clinicians with a new way to identify people who are at high risk for disease. Oxford "Obesity-Gene" Group Launches Target For Obesity Researchers Oxford University's technology transfer company, Isis Innovation, has launched range of new assays for obesity research - tools that can be used to identify potential drug candidates. A team led by Oxford's Prof Chris Schofield has developed the assays. They are based on the group's pioneering work which identified a gene and an enzyme strongly implicated in obesity. American Medical Association Adopts New Direct-To-Consumer Genetic Testing Policy Recommendations At its June 17 annual meeting, the American Medical Association (AMA), the largest physician group in the United States, adopted policy recommendations opposing direct-to-consumer (DTC) genetic testing. The recommendations state that a health care professional should be involved in the genetic-testing process, and encourages individuals interested in obtaining genetic testing to contact a health care professional. Reauthorization Of DNA Backlog Grant Program Could Expand Forensic DNA Collection On July 14 the House of Representatives voted to reauthorize the Debbie Smith DNA Backlog Grant Program (HR 5057). The original Debbie Smith Act of 2004, introduced by Rep. Maloney (D-NY), allocated funds to process backlogged DNA evidence, primarily from rape kits, allowing for the potential resolution of cases in which no suspect has been identified. The reauthorization bill, co-sponsored by Rep. Conyers (D-MI) and Rep. Smith (R-TX), would extend the funding to 2014. California State Actions Point To Need For Federal Leadership On Genetic Testing On June 9 California sent letters to 13 genetic-testing companies ordering them to "cease and desist performing genetic testing without licensure or physician order." Some of the companies have since stopped offering direct-to-consumer tests to Californians, while others insist that they are already in compliance with the law and continue to operate in the state. New York State similarly warned companies this spring that they need licenses to accept DNA samples from the state's residents. Duke-NIEHS Team Shows How DNA Repairs May Reshape The Genome Researchers at Duke University Medical Center and at the National Institute of Environmental Health Sciences (NIEHS) have shown how broken sections of chromosomes can recombine to change genomes and spawn new species. "People have discovered high levels of repeated sequences in the genomes of most higher species and spun theories about why there are so many repeats," said Lucas Argueso, Ph.D., a research scholar in Duke's Department of Molecular Genetics and Microbiology. Genetics And Public Policy Center Provides GINA Resources Years of effort on the part of activists, members of Congress, and their staff members culminated in passage of the Genetic Information Nondiscrimination Act (GINA) on May 21, 2008. Studies Describing Novel Approaches To Maximizing Dicer-Substrate Small Interfering RNAs Published Dicerna Pharmaceuticals, Inc., a second generation RNA interference company developing novel therapeutics utilizing proprietary Dicer Substrate Technology?, today announced key studies highlighting the therapeutic potential for Dicer-substrate small interfering RNAs (DsiRNAs). The first study, co-authored by Dicerna co-founder John Rossi, Ph.D. Assortative Mating And The Role Of Phenotypic Plasticity In Male Competition: Implications For Gene Flow Among Host-associated Parasitoid Populations This manuscript investigates mating preference in conjunction with phenotypic plasticity using Aphidius parasitoids adapted to different host species. Males actively attempted to assortatively mate, but actual mating outcomes were strongly influenced by the relative size of the adult males. Results are discussed in the context of assortative mating in combination with the success of migrant males in mitigating gene flow between host-associated parasitoid populations. Maelstrom Quashes Jumping Genes Scientists have known for decades that certain genes (called transposons) can jump around the genome in an individual cell. This activity can be dangerous, however, especially when it arises in cells that produce eggs and sperm. Such changes can threaten the offspring and the success of a species. To ensure the integrity of these cells, nature developed a mechanism to quash this genetic scrambling, but how it works has remained a mystery. MHC-Correlated Odour Preferences In Humans And The Use Of Oral Contraceptives A well-publicised experiment previously showed that women prefer body odour of men who are genetically dissimilar to themselves. In contrast, contraceptive pill-users preferred relatively similar men. If pill-use alters preferences and choice of partner, resulting between-partner genetic similarity could cause fertility issues, but the difference might alternatively be due to unrelated differences between pill-users and non-users.

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